ZenToks Publication

Chapter 19

The physiological effects of remifentanil on hemodynamic stability during elective surgery

Abstract/Preface

The general anaesthesia inductions may cause hemodynamics disturbance. These responses are often suppressed by administration of remifentanil. In this study the aim is to assess the effects of infusion Remifentanil on hemodynamic stability during general anesthesia. This prospective study we collect 50 healthy patients aged between 20 to 65 years scheduled for elective surgery in Baghdad teaching hospital with ASA, (I. II). All these patients received 1 mcg/kg/min remifentanil by continuous infusion over 30 minutes. The recording of mean arterial, heart rate, respiratory rate and peripheral oxygen saturation 10, 5 minutes pre-induction, throughout infusion and at 5, 10, 15 Minutes after induction. The results showed decreases in heart rate and blood pressure values during infusion of Remifentanil and the value started to increase after the infusion is stopped. The respiratory rate and SpO2 (peripheral O2 saturation) values reminded in the same limits during and after infusion of Remifentanil with no major changes. Remifentanil infusion affectively attenuate the hemodynamic response of the heart rate and blood pressure and there was significant decrease in them during infusion with no significant effect on respiratory rate and peripheral oxygen saturation.